Dr. Marianne Koritzinsky Publications

  1. Talmor, B, Marastoni, S, Lau, B, Yam, AO, Yeung, N, Lin, HM, Li, ZJ, Woo, H, Pranavan, G, Stricker, PD et al. (2026). A phase I study of hydroxychloroquine and suba-itraconazole in men with biochemical relapse of prostate cancer (HITMAN-PC): dose escalation results. Cancer Res Commun,.
  2. Poulton, E, Desjardins, A, Harding, SM, Malbeteau, L, Koritzinsky, M (2026). Cytosolic DNA in radiotherapy: relevance, mechanisms, and detection. Radiother Oncol214,111220.
  3. Yang, R, Koritzinsky, M, Wu, XY, Milosevic, M (2025). Theranostic potential of manganese dioxide nanoparticles for targeting tumor hypoxia during MR-guided radiotherapy. Int J Radiat Biol,1-8.
  4. Koritzinsky, M, Wouters, BG, Milosevic, M (2025). New developments in hypoxia-directed patient selection and stratification in radiotherapy. Int J Radiat Biol,1-7.
  5. Xu, X, Zhu, H, Hugh-White, R, Livingstone, J, Eng, S, Zeltser, N, Wang, Y, Pajdzik, K, Chen, S, Houlahan, KE et al. (2025). The landscape of N-methyladenosine in localized primary prostate cancer. Nat Genet57,934-948.
  6. Zeinizade, E, Yousefalizideh, G, Aminfar, P, Horn, M, Ding, L, Pires, L, Jaglanian, A, Malbeteau, L, Harrington, K, Calçada, C et al. (2025). Atomically-precise Au(Lys-Cys-Lys) nanoclusters for radiation sensitization. J Nanobiotechnology23,185.
  7. Koontz, BF, Koritzinsky, M, Zoberi, JE, Brown, SL, Ding, X, Wong, J, Joiner, MC, Dominello, MM, Burmeister, J (2024). Three discipline collaborative radiation therapy (3DCRT) special debate: Systemic radiotherapy using targeted isotopes is the best hope for advancing curative radiation therapy. J Appl Clin Med Phys25,e14533.
  8. Lee, SCS, Pyo, AHA, Mohammadi, H, Zhang, J, Dvorkin-Gheva, A, Malbeteau, L, Chung, S, Khan, S, Ciudad, MT, Rondeau, V et al. (2024). Cysteamine dioxygenase (ADO) governs cancer cell mitochondrial redox homeostasis through proline metabolism. Sci Adv10,eadq0355.
  9. Ci, X, Chen, S, Zhu, R, Zarif, M, Jain, R, Guo, W, Ramotar, M, Gong, L, Xu, W, Singh, O et al. (2024). Oral pimonidazole unveils clinicopathologic and epigenetic features of hypoxic tumour aggressiveness in localized prostate cancer. BMC Cancer24,744.
  10. Ciudad, MT, Quevedo, R, Lamorte, S, Jin, R, Nzirorera, N, Koritzinsky, M, McGaha, TL (2024). Dabrafenib Alters MDSC Differentiation and Function by Activation of GCN2. Cancer Res Commun4,765-784.
  11. Lee, SCS, Pyo, AHA, Koritzinsky, M (2023). Longitudinal dynamics of the tumor hypoxia response: From enzyme activity to biological phenotype. Sci Adv9,eadj6409.
  12. Ciudad, MT, Quevedo, R, Lamorte, S, Jin, R, Nzirorera, N, Koritzinsky, M, McGaha, TL (2023). Dabrafenib alters MDSC differentiation and function by activation of GCN2. bioRxiv,.
  13. Jiang, Z, Ju, Y, Ali, A, Chung, PED, Skowron, P, Wang, DY, Shrestha, M, Li, H, Liu, JC, Vorobieva, I et al. (2023). Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer. Nat Commun14,4313.
  14. Kondratyev, M, Pesic, A, Ketela, T, Stickle, N, Beswick, C, Shalev, Z, Marastoni, S, Samadian, S, Dvorkin-Gheva, A, Sayad, A et al. (2023). Identification of acquired Notch3 dependency in metastatic Head and Neck Cancer. Commun Biol6,538.
  15. Marastoni, S, Madariaga, A, Pesic, A, Nair, SN, Li, ZJ, Shalev, Z, Ketela, T, Colombo, I, Mandilaras, V, Cabanero, M et al. (2022). Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer. Cancer Res Commun2,293-306.
  16. Han, K, Fyles, A, Shek, T, Croke, J, Dhani, N, D'Souza, D, Lee, TY, Chaudary, N, Bruce, J, Pintilie, M et al. (2022). A Phase II Randomized Trial of Chemoradiation with or without Metformin in Locally Advanced Cervical Cancer. Clin Cancer Res28,5263-5271.
  17. Dimitriou, ID, Meiri, D, Jitkova, Y, Elford, AR, Koritzinsky, M, Schimmer, AD, Ohashi, PS, Sonenberg, N, Rottapel, R (2022). Translational Control by 4E-BP1/2 Suppressor Proteins Regulates Mitochondrial Biosynthesis and Function during CD8 T Cell Proliferation. J Immunol208,2702-2712.
  18. Lam, KHB, Leon, AJ, Hui, W, Lee, SC, Batruch, I, Faust, K, Klekner, A, Hutóczki, G, Koritzinsky, M, Richer, M et al. (2022). Topographic mapping of the glioblastoma proteome reveals a triple-axis model of intra-tumoral heterogeneity. Nat Commun13,116.
  19. Wong, CS, Chu, W, Ashamalla, S, Fenech, D, Berry, S, Kiss, A, Koritzinsky, M (2021). Metformin with neoadjuvant chemoradiation to improve pathologic response in rectal cancer: A pilot phase I/II trial. Clin Transl Radiat Oncol30,60-64.
  20. Mahendralingam, MJ, Kim, H, McCloskey, CW, Aliar, K, Casey, AE, Tharmapalan, P, Pellacani, D, Ignatchenko, V, Garcia-Valero, M, Palomero, L et al. (2021). Mammary epithelial cells have lineage-rooted metabolic identities. Nat Metab3,665-681.
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