Darren Rodenhizer, Edoardo Gaude, Dan Cojocari, Radhakrishnan Mahadevan, Christian Frezza, Bradly G. Wouters & Alison P. McGuigan Nature Materials (2015) Full Text on ResearchGate Abstract The profound […]
Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER Twan van den Beucken, Elizabeth Koch, Kenneth
J Enzyme Inhib Med Chem. 2014 Oct 27:1-33. Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology
Ramaekers CH, van den Beucken T, Bristow RG, Chiu RK, Durocher D, Wouters BG. PLoS One. 2014 Feb 28;9(2):e89997. doi: 10.1371/journal.pone.0089997. eCollection 2014. Abstract The cellular
Clin Cancer Res. 2013 Dec 15;19(24):6741-50. doi: 10.1158/1078-0432.CCR-13-1787. Epub 2013 Oct 18. Zannella VE1, Dal Pra A, Muaddi H, McKee TD, Stapleton S, Sykes J, Glicksman R, Chaib
Koritzinsky M, Levitin F, van den Beucken T, Rumantir RA, Harding NJ, Chu KC, Boutros PC, Braakman I, Wouters BG. J Cell Biol. 2013 Nov 18. Full text. Abstract Most
Hypoxic Activation of the PERK/eIF2α Arm of the Unfolded Protein Response Promotes Metastasis through Induction of LAMP3 Mujcic H, Nagelkerke A, Rouschop
Contributions of AMPK and p53 dependent signaling to radiation response in the presence of metformin. Muaddi H, Chowdhury S, Vellanki R, Zamiara P, Koritzinsky M.
The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia. Schaaf MB, Cojocari Dan , Keulers TG, Jutten B, Starmans MH, de Jong MC, Begg
New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and