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Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction

hypoxia / June 13, 2011

Kasper M. A. Rouschop, Ludwig Dubois, Marco B. E. Schaaf, Twan van den Beucken, Natasja Lieuwes, Tom G. H. Keulers, Kim G. M. Savelkouls, Johan Bussink, Albert J. […]

Publications

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

hypoxia / January 4, 2010

Kasper M.A. Rouschop, Twan van den Beucken, Ludwig Dubois, Hanneke Niessen, Johan Bussink, Kim Savelkouls, Tom Keulers, Hilda Mujcic, Willy

Publications

“Hypoxia signalling through mTOR and the unfolded protein response in cancer” Nature Rev. Cancer, 2008

hypoxia / November 6, 2008

Bradly G. Wouters & Marianne Koritzinsky [button url=”http://www.nature.com/nrc/journal/v8/n11/abs/nrc2501.html#top” ]Read online[/button] Abstract Hypoxia occurs in the majority of tumours, promoting angiogenesis, metastasis

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